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Inhibition of heregulin mediated MCF-7 breast cancer cell growth by the ErbB3 binding Protein EBP1

The ErbB2/3 heterodimer plays a critical role in breast cancer genesis and progression. EBP1, an ErbB3 binding protein, inhibits breast cancer growth but its effects on ErbB3 ligand mediated signal transduction or ErbB receptors is not known. We report here that ectopic expression of EBP1 in MCF-7 a...

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Autors principals: Zhang, Yuexing, Akinmade, Damilola, Hamburger, Anne W.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2464455/
https://ncbi.nlm.nih.gov/pubmed/18355957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2008.02.024
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