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The Population and Evolutionary Dynamics of Phage and Bacteria with CRISPR–Mediated Immunity

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), together with associated genes (cas), form the CRISPR–cas adaptive immune system, which can provide resistance to viruses and plasmids in bacteria and archaea. Here, we use mathematical models, population dynamic experiments, and DN...

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Autori principali: Levin, Bruce R., Moineau, Sylvain, Bushman, Mary, Barrangou, Rodolphe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597502/
https://ncbi.nlm.nih.gov/pubmed/23516369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003312
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