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The Population and Evolutionary Dynamics of Phage and Bacteria with CRISPR–Mediated Immunity

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), together with associated genes (cas), form the CRISPR–cas adaptive immune system, which can provide resistance to viruses and plasmids in bacteria and archaea. Here, we use mathematical models, population dynamic experiments, and DN...

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Bibliografiske detaljer
Main Authors: Levin, Bruce R., Moineau, Sylvain, Bushman, Mary, Barrangou, Rodolphe
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597502/
https://ncbi.nlm.nih.gov/pubmed/23516369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003312
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