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Dealing with the Evolutionary Downside of CRISPR Immunity: Bacteria and Beneficial Plasmids

The immune systems that protect organisms from infectious agents invariably have a cost for the host. In bacteria and archaea CRISPR-Cas loci can serve as adaptive immune systems that protect these microbes from infectiously transmitted DNAs. When those DNAs are borne by lytic viruses (phages), this...

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Detalhes bibliográficos
Main Authors: Jiang, Wenyan, Maniv, Inbal, Arain, Fawaz, Wang, Yaying, Levin, Bruce R., Marraffini, Luciano A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784566/
https://ncbi.nlm.nih.gov/pubmed/24086164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003844
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