Prevention of JNK phosphorylation as a mechanism for rosiglitazone in neuroprotection after transient cerebral ischemia: activation of dual specificity phosphatase

Rosiglitazone, a synthetic peroxisome proliferator-activated receptor-γ (PPARγ) agonist, prevents cell death after cerebral ischemia in animal models, but the underlying mechanism has not been clarified. In this study, we examined how rosiglitazone protects neurons against ischemia. Mice treated wit...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Okami, Nobuya, Narasimhan, Purnima, Yoshioka, Hideyuki, Sakata, Hiroyuki, Kim, Gab Seok, Jung, Joo Eun, Maier, Carolina M, Chan, Pak H
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597369/
https://ncbi.nlm.nih.gov/pubmed/23032483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.138
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares