Prevention of JNK phosphorylation as a mechanism for rosiglitazone in neuroprotection after transient cerebral ischemia: activation of dual specificity phosphatase

Rosiglitazone, a synthetic peroxisome proliferator-activated receptor-γ (PPARγ) agonist, prevents cell death after cerebral ischemia in animal models, but the underlying mechanism has not been clarified. In this study, we examined how rosiglitazone protects neurons against ischemia. Mice treated wit...

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Detaylı Bibliyografya
Asıl Yazarlar: Okami, Nobuya, Narasimhan, Purnima, Yoshioka, Hideyuki, Sakata, Hiroyuki, Kim, Gab Seok, Jung, Joo Eun, Maier, Carolina M, Chan, Pak H
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2013
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597369/
https://ncbi.nlm.nih.gov/pubmed/23032483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.138
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