Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1

Epithelial cell invasion through the extracellular matrix (ECM) is a crucial step in branching morphogenesis. The mechanisms by which the mammary epithelium integrates cues from the ECM with intracellular signaling in order to coordinate invasion through the stroma to make the mammary tree are poorl...

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Detalhes bibliográficos
Main Authors: Mori, Hidetoshi, Lo, Alvin T., Inman, Jamie L., Alcaraz, Jordi, Ghajar, Cyrus M., Mott, Joni D., Nelson, Celeste M., Chen, Connie S., Zhang, Hui, Bascom, Jamie L., Seiki, Motoharu, Bissell, Mina J.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597211/
https://ncbi.nlm.nih.gov/pubmed/23250208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.084236
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