Human IGF1 extends lifespan and enhances resistance to Plasmodium falciparum infection in the malaria vector Anopheles stephensi

The highly conserved insulin/insulin-like growth factor (IGF) signaling (IIS) pathway regulates metabolism, development, lifespan and immunity across a wide range of organisms. Previous studies have shown that human insulin ingested in the blood meal can activate mosquito IIS, resulting in attenuate...

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Bibliographic Details
Main Authors: Drexler, Anna, Nuss, Andrew, Hauck, Eric, Glennon, Elizabeth, Cheung, Kong, Brown, Mark, Luckhart, Shirley
Format: Artigo
Language:Inglês
Published: Company of Biologists 2013
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597202/
https://ncbi.nlm.nih.gov/pubmed/23255191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jeb.078873
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