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Quantifying the transcriptional output of single alleles in single living mammalian cells

Transcription kinetics of actively transcribing genes in vivo have generally been measured using tandem gene arrays. However, tandem arrays do not reflect the endogenous state of genome organization where genes appear as single alleles. We present here a robust technique for the quantification of mR...

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Bibliografske podrobnosti
Main Authors: Yunger, Sharon, Rosenfeld, Liat, Garini, Yuval, Shav-Tal, Yaron
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597184/
https://ncbi.nlm.nih.gov/pubmed/23424748
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