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Quantifying β-catenin subcellular dynamics and cyclin D1 mRNA transcription during Wnt signaling in single living cells

Signal propagation from the cell membrane to a promoter can induce gene expression. To examine signal transmission through sub-cellular compartments and its effect on transcription levels in individual cells within a population, we used the Wnt/β-catenin signaling pathway as a model system. Wnt sign...

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Podrobná bibliografie
Vydáno v:eLife
Hlavní autoři: Kafri, Pinhas, Hasenson, Sarah E, Kanter, Itamar, Sheinberger, Jonathan, Kinor, Noa, Yunger, Sharon, Shav-Tal, Yaron
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161448/
https://ncbi.nlm.nih.gov/pubmed/27879202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.16748
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