Reduction of pro-tumorigenic activity of human prostate cancer-associated fibroblasts using Dlk1 or SCUBE1

Human prostatic cancer-associated fibroblasts (CAFs) can elicit malignant changes in initiated but non-tumorigenic human prostate epithelium, demonstrating that they possess pro-tumorigenic properties. We set out to reduce the pro-tumorigenic activity of patient CAFs using the Dlk1 and SCUBE1 molecu...

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Detalhes bibliográficos
Main Authors: Orr, Brigid, Grace, O. Cathal, Brown, Pam, Riddick, Antony C. P., Stewart, Grant D., Franco, Omar E., Hayward, Simon W., Thomson, Axel A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2013
Assuntos:
Research Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597035/
https://ncbi.nlm.nih.gov/pubmed/23136397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.010355
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