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Deletion of calcineurin promotes a pro-tumorigenic fibroblast phenotype

Fibroblast activation is a crucial step in tumor growth and metastatic progression. Activated fibroblasts remodel the extracellular matrix (ECM) in primary tumor and metastatic microenvironments, exerting both pro- and anti-tumorigenic effects. However, the intrinsic mechanisms that regulate the act...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cancer Res
Päätekijät: Lieberman, Allyson, Barrett, Richard, Kim, Jaewon, Zhang, Kathy L., Avery, Diana, Monslow, James, Kim, Hyunsoo, Kim, Bang-Jin, Pure, Ellen, Ryeom, Sandra
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679769/
https://ncbi.nlm.nih.gov/pubmed/31189649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-0056
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