Cell culture and Drosophila model systems define three classes of anaplastic lymphoma kinase mutations in neuroblastoma

Neuroblastoma is a childhood extracranial solid tumour that is associated with a number of genetic changes. Included in these genetic alterations are mutations in the kinase domain of the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase (RTK), which have been found in both somatic and famil...

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Autors principals: Chand, Damini, Yamazaki, Yasuo, Ruuth, Kristina, Schönherr, Christina, Martinsson, Tommy, Kogner, Per, Attiyeh, Edward F., Maris, John, Morozova, Olena, Marra, Marco A., Ohira, Miki, Nakagawara, Akira, Sandström, Per-Erik, Palmer, Ruth H., Hallberg, Bengt
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Limited 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597019/
https://ncbi.nlm.nih.gov/pubmed/23104988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.010348
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