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Functional modeling in zebrafish demonstrates that the atrial-fibrillation-associated gene GREM2 regulates cardiac laterality, cardiomyocyte differentiation and atrial rhythm

Atrial fibrillation (AF) is the most common cardiac arrhythmia and carries a significant risk of stroke and heart failure. The molecular etiologies of AF are poorly understood, leaving patients with limited therapeutic options. AF has been recognized as an inherited disease in almost 30% of patient...

詳細記述

保存先:
書誌詳細
主要な著者: Müller, Iris I., Melville, David B., Tanwar, Vineeta, Rybski, Witold M., Mukherjee, Amrita, Shoemaker, M. Benjamin, Wang, Wan-Der, Schoenhard, John A., Roden, Dan M., Darbar, Dawood, Knapik, Ela W., Hatzopoulos, Antonis K.
フォーマット: Artigo
言語:Inglês
出版事項: The Company of Biologists Limited 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597016/
https://ncbi.nlm.nih.gov/pubmed/23223679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.010488
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