Functional modeling in zebrafish demonstrates that the atrial-fibrillation-associated gene GREM2 regulates cardiac laterality, cardiomyocyte differentiation and atrial rhythm

Atrial fibrillation (AF) is the most common cardiac arrhythmia and carries a significant risk of stroke and heart failure. The molecular etiologies of AF are poorly understood, leaving patients with limited therapeutic options. AF has been recognized as an inherited disease in almost 30% of patient...

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Detalhes bibliográficos
Main Authors: Müller, Iris I., Melville, David B., Tanwar, Vineeta, Rybski, Witold M., Mukherjee, Amrita, Shoemaker, M. Benjamin, Wang, Wan-Der, Schoenhard, John A., Roden, Dan M., Darbar, Dawood, Knapik, Ela W., Hatzopoulos, Antonis K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597016/
https://ncbi.nlm.nih.gov/pubmed/23223679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.010488
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