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Activation and desensitization of TRPV1 channels in sensory neurons by the PPARα agonist palmitoylethanolamide

BACKGROUND AND PURPOSE: Palmitoylethanolamide (PEA) is an endogenous fatty acid amide displaying anti-inflammatory and analgesic actions. To investigate the molecular mechanism responsible for these effects, the ability of PEA and of pain-inducing stimuli such as capsaicin (CAP) or bradykinin (BK) t...

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Detalhes bibliográficos
Main Authors: Ambrosino, Paolo, Soldovieri, Maria Virginia, Russo, Claudio, Taglialatela, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596648/
https://ncbi.nlm.nih.gov/pubmed/23083124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12029
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