Activation of Kv7 Potassium Channels Inhibits Intracellular Ca(2+) Increases Triggered By TRPV1-Mediated Pain-Inducing Stimuli in F11 Immortalized Sensory Neurons

Kv7.2-Kv7.5 channels mediate the M-current (I(KM)), a K(+)-selective current regulating neuronal excitability and representing an attractive target for pharmacological therapy against hyperexcitability diseases such as pain. Kv7 channels interact functionally with transient receptor potential vanill...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ambrosino, Paolo, Soldovieri, Maria Virginia, Di Zazzo, Erika, Paventi, Gianluca, Iannotti, Fabio Arturo, Mosca, Ilaria, Miceli, Francesco, Franco, Cristina, Canzoniero, Lorella Maria Teresa, Taglialatela, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769798/
https://ncbi.nlm.nih.gov/pubmed/31487785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20184322
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