Llwytho...

Impaired Transport of Mitochondrial Transcription Factor and the Metabolic Memory Phenomenon Associated with the Progression of Diabetic Retinopathy

Diabetes damages retinal mitochondrial DNA (mtDNA), and compromises the mtDNA transcription. In the transcription and replication of mtDNA, nuclear-encoded transcription factor A (TFAM) is considered as a key activator, and we have shown that in diabetes while retinal TFAM gene expression is increas...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Santos, Julia M., Kowluru, Renu A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596457/
https://ncbi.nlm.nih.gov/pubmed/23255365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dmrr.2384
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