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Overlapping elements in the guanylate-binding protein gene promoter mediate transcriptional induction by alpha and gamma interferons.

The gene encoding a 67-kDa cytoplasmic guanylate-binding protein (GBP) is transcriptionally induced in cells exposed to interferon of either type I (alpha interferon [IFN-alpha] or type II (IFN-gamma). The promoter of the GBP gene was cloned and found to contain an IFN-alpha-stimulated response elem...

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Pubblicato in:Mol Cell Biol
Autori principali: Lew, D J, Decker, T, Strehlow, I, Darnell, J E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1991
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359608/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1898761/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.1.182-191.1991
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