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Deletion or substitution within the alpha platelet-derived growth factor receptor kinase insert domain: effects on functional coupling with intracellular signaling pathways.

The tyrosine kinase domains of the platelet-derived growth factor (PDGF) and colony-stimulating factor-1 (CSF-1)/c-fms receptors are interrupted by kinase inserts (ki) which vary in length and amino acid sequence. To define the role of the ki in the human alpha PDGF receptor (alpha PDGFR), we genera...

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Bibliografiske detaljer
Main Authors: Heidaran, M A, Pierce, J H, Lombardi, D, Ruggiero, M, Gutkind, J S, Matsui, T, Aaronson, S A
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC359603/
https://ncbi.nlm.nih.gov/pubmed/1702511
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