Deletion or substitution within the alpha platelet-derived growth factor receptor kinase insert domain: effects on functional coupling with intracellular signaling pathways.

The tyrosine kinase domains of the platelet-derived growth factor (PDGF) and colony-stimulating factor-1 (CSF-1)/c-fms receptors are interrupted by kinase inserts (ki) which vary in length and amino acid sequence. To define the role of the ki in the human alpha PDGF receptor (alpha PDGFR), we genera...

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Detalhes bibliográficos
Main Authors: Heidaran, M A, Pierce, J H, Lombardi, D, Ruggiero, M, Gutkind, J S, Matsui, T, Aaronson, S A
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC359603/
https://ncbi.nlm.nih.gov/pubmed/1702511
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