Microprocessor, Setx, Xrn2, and Rrp6 Co-operate to Induce Premature Termination of Transcription by RNAPII

Transcription elongation is increasingly recognized as an important mechanism of gene regulation. Here, we show that microprocessor controls gene expression in an RNAi-independent manner. Microprocessor orchestrates the recruitment of termination factors Setx and Xrn2, and the 3′–5′ exoribonuclease,...

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Autors principals: Wagschal, Alexandre, Rousset, Emilie, Basavarajaiah, Poornima, Contreras, Xavier, Harwig, Alex, Laurent-Chabalier, Sabine, Nakamura, Mirai, Chen, Xin, Zhang, Ke, Meziane, Oussama, Boyer, Frédéric, Parrinello, Hugues, Berkhout, Ben, Terzian, Christophe, Benkirane, Monsef, Kiernan, Rosemary
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595997/
https://ncbi.nlm.nih.gov/pubmed/22980978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.08.004
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