Microprocessor, Setx, Xrn2, and Rrp6 Co-operate to Induce Premature Termination of Transcription by RNAPII

Transcription elongation is increasingly recognized as an important mechanism of gene regulation. Here, we show that microprocessor controls gene expression in an RNAi-independent manner. Microprocessor orchestrates the recruitment of termination factors Setx and Xrn2, and the 3′–5′ exoribonuclease,...

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Detalhes bibliográficos
Main Authors: Wagschal, Alexandre, Rousset, Emilie, Basavarajaiah, Poornima, Contreras, Xavier, Harwig, Alex, Laurent-Chabalier, Sabine, Nakamura, Mirai, Chen, Xin, Zhang, Ke, Meziane, Oussama, Boyer, Frédéric, Parrinello, Hugues, Berkhout, Ben, Terzian, Christophe, Benkirane, Monsef, Kiernan, Rosemary
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595997/
https://ncbi.nlm.nih.gov/pubmed/22980978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.08.004
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