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Transcriptional induction of the human asparagine synthetase gene during the unfolded protein response does not require the ATF6 and IRE1/XBP1 arms of the pathway

The UPR (unfolded protein response) pathway is comprised of three signalling cascades mediated by the ER (endoplasmic reticulum) stress sensor proteins PERK [PKR (double-stranded RNA-activated protein kinase)-like ER kinase], IRE1 (inositol-requiring kinase 1) and ATF6 (activating transcription fact...

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Detalhes bibliográficos
Main Authors: Gjymishka, Altin, Su, Nan, Kilberg, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595601/
https://ncbi.nlm.nih.gov/pubmed/18840095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20081706
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