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Argonaute Divides Its RNA Guide into Domains with Distinct Functions and RNA-Binding Properties
MicroRNAs (miRNAs) and small interfering RNAs (siRNAs) guide Argonaute proteins to silence mRNA expression. Argonaute binding alters the properties of an RNA guide, creating functional domains. We show that the domains established by Argonaute— the anchor, seed, central, 3′ supplementary, and tail r...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3595543/ https://ncbi.nlm.nih.gov/pubmed/23178124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.10.036 |
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