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Argonaute protein identity and pairing geometry determine cooperativity in mammalian RNA silencing
Small RNAs loaded into Argonaute proteins direct silencing of complementary target mRNAs. It has been proposed that multiple, imperfectly complementary small interfering RNAs or microRNAs, when bound to the 3′ untranslated region of a target mRNA, function cooperatively to silence target expression....
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3185918/ https://ncbi.nlm.nih.gov/pubmed/21878547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2778911 |
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