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Argonaute protein identity and pairing geometry determine cooperativity in mammalian RNA silencing
Small RNAs loaded into Argonaute proteins direct silencing of complementary target mRNAs. It has been proposed that multiple, imperfectly complementary small interfering RNAs or microRNAs, when bound to the 3′ untranslated region of a target mRNA, function cooperatively to silence target expression....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3185918/ https://ncbi.nlm.nih.gov/pubmed/21878547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2778911 |
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