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Gene expression signature-based approach identifies a pro-resolving mechanism of action for histone deacetylase inhibitors

Despite several therapies being currently available to treat inflammatory diseases, new drugs to treat chronic conditions with less side effects and lower production costs are still needed. An innovative approach to drug discovery, the Connectivity Map (CMap), shows how integrating genome-wide gene...

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Detalhes bibliográficos
Main Authors: Montero-Melendez, T, Dalli, J, Perretti, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595482/
https://ncbi.nlm.nih.gov/pubmed/23222458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.154
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