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Interspecies molecular chimeras of kit help define the binding site of the stem cell factor.
The extracellular portion of the kit-encoded receptor for the stem cell factor (SCF) comprises five immunoglobulin (Ig)-like domains. To localize the ligand recognition site, we exploited the lack of binding of human SCF to the murine receptor by using human-mouse hybrids of Kit and species-specific...
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| Vydáno v: | Mol Cell Biol |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
1993
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359543/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7681144/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.4.2224 |
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