Interspecies molecular chimeras of kit help define the binding site of the stem cell factor.

The extracellular portion of the kit-encoded receptor for the stem cell factor (SCF) comprises five immunoglobulin (Ig)-like domains. To localize the ligand recognition site, we exploited the lack of binding of human SCF to the murine receptor by using human-mouse hybrids of Kit and species-specific...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Lev, S, Blechman, J, Nishikawa, S, Givol, D, Yarden, Y
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359543/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7681144/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.4.2224-2234.1993
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