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Interspecies molecular chimeras of kit help define the binding site of the stem cell factor.

The extracellular portion of the kit-encoded receptor for the stem cell factor (SCF) comprises five immunoglobulin (Ig)-like domains. To localize the ligand recognition site, we exploited the lack of binding of human SCF to the murine receptor by using human-mouse hybrids of Kit and species-specific...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Biol
Prif Awduron: Lev, S, Blechman, J, Nishikawa, S, Givol, D, Yarden, Y
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 1993
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359543/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7681144/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.4.2224-2234.1993
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