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Circadian disruption leads to insulin resistance and obesity

BACKGROUND: Disruption of circadian (daily) timekeeping enhances the risk of metabolic syndrome, obesity, and Type 2 diabetes. While clinical observations have suggested that insulin action is not constant throughout the 24 hour cycle, its magnitude and periodicity have not been assessed. Moreover,...

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Detalhes bibliográficos
Main Authors: Shi, Shu-qun, Ansari, Tasneem, McGuinness, Owen P., Wasserman, David H., Johnson, Carl Hirschie
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595381/
https://ncbi.nlm.nih.gov/pubmed/23434278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2013.01.048
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