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Circadian Clock Gene Bmal1 Is Not Essential After All; Functional Replacement with its Paralog, Bmal2
Most of the central circadian clock genes in the mouse exist as paralog pairs (Per1/Per2, Cry1/Cry2, Clock/Npas2) that must both be knocked out to confer arhythmicity [1, 2, 3]. The only exception to this pattern is Bmal1/Mop3, the single knockout of which confers arhythmicity despite the presence o...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2907674/ https://ncbi.nlm.nih.gov/pubmed/20153195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.12.034 |
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