Reduction in Phencyclidine Induced Sensorimotor Gating Deficits in the Rat Following Increased System x(c)(−) Activity in the Medial Prefrontal Cortex

RATIONALE: Aspects of schizophrenia, including deficits in sensorimotor gating, have been linked to glutamate dysfunction and/or oxidative stress in the prefrontal cortex. System x(c)(−), a cystine- glutamate antiporter, is a poorly understood mechanism that contributes to both cellular antioxidant...

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Hlavní autoři: Lutgen, Victoria, Qualmann, Krista, Resch, Jon, Kong, Linghai, Choi, SuJean, Baker, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595356/
https://ncbi.nlm.nih.gov/pubmed/23192314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-012-2926-3
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