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Chronic Phencyclidine Increases Synapsin-1 and Synaptic Adaptation Proteins in the Medial Prefrontal Cortex

Phencyclidine (PCP) mimics many aspects of schizophrenia, yet the underlying mechanism of neurochemical adaptation for PCP is unknown. We therefore used proteomics to study changes in the medial prefrontal cortex in animals with PCP-induced behavioural deficits. Male Wistar rats were injected with s...

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Autori principali: Pickering, Chris, Ericson, Mia, Söderpalm, Bo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658391/
https://ncbi.nlm.nih.gov/pubmed/23738220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/620361
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