Chronic Phencyclidine Increases Synapsin-1 and Synaptic Adaptation Proteins in the Medial Prefrontal Cortex

Phencyclidine (PCP) mimics many aspects of schizophrenia, yet the underlying mechanism of neurochemical adaptation for PCP is unknown. We therefore used proteomics to study changes in the medial prefrontal cortex in animals with PCP-induced behavioural deficits. Male Wistar rats were injected with s...

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Main Authors: Pickering, Chris, Ericson, Mia, Söderpalm, Bo
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658391/
https://ncbi.nlm.nih.gov/pubmed/23738220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/620361
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