Aberrant Schwann Cell Lipid Metabolism Linked to Mitochondrial Deficits Leads to Axon Degeneration and Neuropathy

Mitochondrial dysfunction is a common cause of peripheral neuropathy. Much effort has been devoted to examining the role played by neuronal/axonal mitochondria, but how mitochondrial deficits in peripheral nerve glia (Schwann cells, SCs) contribute to peripheral nerve diseases remains unclear. Here,...

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Главные авторы: Viader, Andreu, Sasaki, Yo, Kim, Sungsu, Strickland, Amy, Workman, Cayce S., Yang, Kui, Gross, Richard W., Milbrandt, Jeffrey
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594792/
https://ncbi.nlm.nih.gov/pubmed/23473319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.01.012
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