A functional variomics tool for discovering drug resistance genes and drug targets

Comprehensive discovery of genetic mechanisms of drug resistance and identification of in vivo drug targets represent significant challenges. Here we present a functional variomics technology in the model organism Saccharomyces cerevisiae. This tool analyzes numerous genetic variants and effectively...

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Autores principales: Huang, Zhiwei, Chen, Kaifu, Zhang, Jianhuai, Li, Yongxiang, Wang, Hui, Cui, Dandan, Tang, Jiangwu, Liu, Yong, Shi, Xiaomin, Li, Wei, Liu, Dan, Chen, Rui, Sucgang, Richard S., Pan, Xuewen
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594652/
https://ncbi.nlm.nih.gov/pubmed/23416056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.01.019
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