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NAAG peptidase inhibitors and deletion of NAAG peptidase gene enhance memory in novel object recognition test

The peptide neurotransmitter N-acetylaspartylglutamate (NAAG) is inactivated by the extracellular enzyme glutamate carboxypeptidase II. Inhibitors of this enzyme reverse dizocilpine (MK-801)-induced impairment of short-term memory in the novel object recognition test. The objective of this study was...

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Autori principali: Janczura, Karolina J., Olszewski, Rafal T., Bzdega, Tomasz, Bacich, Dean J., Heston, Warren D., Neale, Joseph H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594592/
https://ncbi.nlm.nih.gov/pubmed/23200894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2012.11.027
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