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Isolation and characterization of DNA sequences that are specifically bound by wild-type p53 protein.

Wild-type p53 was shown to function as a transcription factor. The N-terminal region of the protein contains the transcription activation domain, while the C terminus is responsible for DNA binding. Localization of the DNA-binding domain of the p53 protein to the highly conserved carboxy-terminal re...

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Autors principals: Foord, O, Navot, N, Rotter, V
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC359447/
https://ncbi.nlm.nih.gov/pubmed/8441383
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