All-or-none Suppression of B Cell Terminal Differentiation by Environmental Contaminant 2,3,7,8-Tetrachlorodibenzo-p-Dioxin

Many environmental contaminants can disrupt the adaptive immune response. Exposure to the ubiquitous aryl hydrocarbon receptor (AhR) ligand 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and other agonists suppresses the antibody response. The underlying pathway mechanism by which TCDD alters B cell fun...

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Detalhes bibliográficos
Main Authors: Zhang, Qiang, Kline, Douglas E., Bhattacharya, Sudin, Crawford, Robert B., Conolly, Rory B., Thomas, Russell S., Andersen, Melvin E., Kaminski, Norbert E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594464/
https://ncbi.nlm.nih.gov/pubmed/23357550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2013.01.015
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