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A novel pathway of presentation by class II-MHC molecules involving peptides or denatured proteins important in autoimmunity
We describe here a pathway of presentation involving peptides or denatured proteins that generate unique peptide-MHC complexes. Such complexes select for non-conventional CD4 T cells. We have examined this pathway and the corresponding CD4 T cells in diabetic autoimmunity. Autoimmunity requires both...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3594457/ https://ncbi.nlm.nih.gov/pubmed/23200226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2012.10.024 |
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