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V(D)J recombination: signal and coding joint resolution are uncoupled and depend on parallel synapsis of the sites.

V(D)J recombination in lymphoid cells is a site-specific process in which the activity of the recombinase enzyme is targeted to signal sequences flanking the coding elements of antigen receptor genes. The order of the steps in this reaction and their mechanistic interdependence are important to the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sheehan, K M, Lieber, M R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1993
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC359445/
https://ncbi.nlm.nih.gov/pubmed/8441381
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