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Temporally Uncoupled Signal and Coding Joint Formation in Human V(D)J Recombination

In vertebrate antigen receptor gene rearrangement, V(D)J recombination events can occur by deletion or by inversion. For deletional events, the signal joint is deleted from the genome. Nearly half of the immunoglobulin light chain genes undergo V(D)J recombination in an inversional manner, and both...

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Publicado en:Mol Immunol
Main Authors: Hsieh, Chih-Lin, Okitsu, Cindy Y., Lieber, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736249/
https://ncbi.nlm.nih.gov/pubmed/33157352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2020.10.010
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