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Elevated rates of force development and MgATP binding in F764L and S532P myosin mutations causing dilated cardiomyopathy
Dilated cardiomyopathy (DCM) is a disease characterized by dilation of the ventricular chambers and reduced contractile function. We examined the contractile performance of chemically-skinned ventricular strips from two heterozygous murine models of DCM-causing missense mutations of myosin, F764L/+...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3594396/ https://ncbi.nlm.nih.gov/pubmed/23313350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2012.12.022 |
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