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Cardiac myosin isoforms exhibit differential rates of MgADP release and MgATP binding detected by myocardial viscoelasticity

We measured myosin crossbridge detachment rate and the rates of MgADP release and MgATP binding in mouse and rat myocardial strips bearing one of the two cardiac myosin heavy chain (MyHC) isoforms. Mice and rats were fed an iodine-deficient, propylthiouracil diet resulting in ~100% expression of β-M...

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Detalhes bibliográficos
Main Authors: Wang, Yuan, Tanner, Bertrand C.W., Lombardo, Andrew T., Tremble, Sarah M., Maughan, David W., VanBuren, Peter, LeWinter, Martin M., Robbins, Jeffrey, Palmer, Bradley M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535576/
https://ncbi.nlm.nih.gov/pubmed/23123290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2012.10.010
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