MAP3K8 kinase regulates myeloma growth by cell-autonomous and non-autonomous mechanisms involving myeloma-associated monocytes/macrophages

Benefit from cytotoxic therapy in myeloma may be limited by the persistence of residual tumour cells within protective niches. We have previously shown that monocytes/macrophages acquire a proinflammatory transcriptional profile in the myeloma microenvironment. Here we report constitutive activation...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hebron, Ellen, Hope, Chelsea, Kim, Jaehyup, Jensen, Jeffrey L., Flanagan, Claire, Bhatia, Neehar, Maroulakou, Ioanna, Mitsiades, Constantine, Miyamoto, Shigeki, Callander, Natalie, Hematti, Peiman, Asimakopoulos, Fotis
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594344/
https://ncbi.nlm.nih.gov/pubmed/23252623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.12175
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