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Modeling boundary conditions for balanced proliferation in metastatic latency

PURPOSE: Nearly half of cancer metastases become clinically evident five or more years after primary tumor treatment; thus metastatic cells survived without emerging for extended periods. This dormancy has been explained by at least two countervailing scenarios: cellular quiescence and balanced prol...

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Detalhes bibliográficos
Main Authors: Taylor, Donald P, Wells, Jakob Z, Savol, Andrej, Chennubhotla, Chakra, Wells, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594128/
https://ncbi.nlm.nih.gov/pubmed/23329811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-3180
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