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The Role of Phosphatases in the Initiation of Skeletal Mineralization
Endochondral ossification is a carefully orchestrated process mediated by promoters and inhibitors of mineralization. Phosphatases are implicated, but their identities and functions remain unclear. Mutations in the tissue-nonspecific alkaline phosphatase (TNAP) gene cause hypophosphatasia, a heritab...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3594124/ https://ncbi.nlm.nih.gov/pubmed/23183786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-012-9672-8 |
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