Novel vaccination modality provides significant protection against mucosal infection by highly pathogenic SIV

Vaccine induced protection against infection by HIV or highly pathogenic and virulent SIV-strains has been limited. Here, in a proof of concept study, we show that a novel vaccine approach significantly protects Rhesus macaques from mucosal infection by the highly pathogenic strain SIV(mac251). We v...

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Detalhes bibliográficos
Main Authors: Strbo, Natasa, Vaccari, Monica, Pahwa, Savita, Kolber, Michael A., Doster, Melvin N., Fisher, Eva, Gonzalez, Louis, Stablein, Donald, Franchini, Genoveffa, Podack, Eckhard R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594107/
https://ncbi.nlm.nih.gov/pubmed/23401588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202655
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