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RENAL AND EXTRA-RENAL ACTIONS OF KLOTHO
Klotho is a single-pass transmembrane protein highly expressed in the kidney. Membrane Klotho protein acts as co-receptor for fibroblast growth factor-23. Its extracellular domain is shed from cell surface and functions as an endocrine substance that exerts multiple renal and extra-renal functions....
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3593734/ https://ncbi.nlm.nih.gov/pubmed/23465499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semnephrol.2012.12.013 |
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